Pharmacology Syllabus [PCI]

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 Pharmacology Syllabus [PCI]

    1.General Pharmacology:

 - History & Scope 

 - IMP Definitions

 - Nature & Source of Drugs

 - Essential Drugs Concept & Routes of Drug Administration

 - Pharmacokinetics: 

                 - Membrane Transport

                 - ADME

                 - Enzyme Induction & Enzyme Inhibition

                 - Kinetics of Elimination

 - Pharmacodynamics:

                - MOA

                - Receptors: Theories, Classification & Regulation

                - Signal Transduction Mechanisms/Transducer Mechanisms

                - Dose Response Relationship

                - Therapeutic Index

                - Combined Effects of Drugs

                - Factors Modifying Drug Action

 - Adverse Drug Reactions [ADR's]

 - Drug Interactions [Pharmacokinetic & Pharmacodynamic]

 - Drug Discovery & Clinical Evaluation of New Drugs

                                                                                                                                                                              

    2.Pharmacology of Drugs Acting on Peripheral Nervous System:

 - Parasympathomimetic

 - Parasympatholytic

 - Sympathomimetics

 - Sympatholytic

                                                                                                                                                                              

    3.Pharmacology of Drugs Acting on Central Nervous System:

 - General Aesthetics & Pre-Aesthetics

 - Sedatives

 - Hypnotics 

 - Centrally Acting Muscle Relaxants

 - Anti-Epileptics

 - Alcohols & Disulfiram

 - Psychopharmacological Agents

 - Drugs Acting on Parkinson's Disease & Alzheimer‘s Disease 

 - CNS Stimulants & Nootropics

 - Opioid Analgesics & Antagonists

                                                                                                                                                                              

    4.Pharmacology of Drugs Acting on Cardio Vascular System[CVS]:

 - Congestive Heart Failure [CHF]

 - Anti-Hypertensive Drugs

 - Anti-anginal Drugs

 - Anti-Arrhythmic Drugs

 - Anti-Hyperlipidemic Drugs

 - Therapy of Shock

 - Hematinics, Coagulants & Anticoagulants

 - Fibrinolytics & Anti-Platelet Drugs

 - Plasma Volume Expanders

                                                                                                                                                                              

    5.Pharmacology of Drugs Acting on Urinary System:

 - Diuretics

 - Anti-Diuretics

                                                                                                                                                                              

    6.Pharmacology of Drugs Acting on Endocrine System:

 - Anterior Pituitary Hormones-Analogues & their Inhibitors

 - Thyroid Hormones-Analogues & their Inhibitors

 - Hormones Regulating Plasma Calcium Level

 - Insulin, Oral Hypoglycemic Agents & Glucagon

 - ACTH & Corticosteroids

 - Androgens & Anabolic Steroids

 - Estrogens, Progesterone & Oral Contraceptives

 - Drugs Acting on Uterus

                                                                                                                                                                              

    7.Pharmacology of Drugs acting on Respiratory System:

 - Anti-Asthmatic Drugs

 - Drugs Used in Management of COPD

 - Expectorants & Antitussives

 - Nasal Decongestants

 - Respiratory Stimulants

                                                                                                                                                                              

    8.Pharmacology of Drugs Acting on Gastrointestinal Tract:

 - Antiulcer Agents

 - Drugs for Constipation & Diarrhoea

 - Appetite Stimulants & Suppressants

 - Digestants & Carminatives

 - Emetics & Anti-Emetics

                                                                                                                                                                              

    9.Autocoids & Related Drugs:

 - Histamine, 5-HT & their Antagonists

 - Prostaglandins

 - Angiotensin, Bradykinin & Substance P

 - Non-Steroidal Anti-Inflammatory Agents [NSAID]

 - Anti-Gout Drugs

 - Antirheumatic Drugs

                                                                                                                                                                              

    10.Chemotherapy:

 - Antitubercular Agents

 - Antileprotic Agents

 - Antifungal Agents

 - Antiviral Drugs

 - Anthelmintics

 - Antimalarial Drugs

 - Antiamoebic Agents

 - Urinary Tract Infections[UTI’s] & Sexually Transmitted Diseases[STD’s]

 - Chemotherapy of Malignancy

                                                                                                                                                                              

    11.Immunopharmacology:

 - Immunostimulants

 - Immunosuppressant

                                                                                                                                                                              

    12.Principles of Toxicology:

 - Genotoxicity

 - Carcinogenicity

 - Teratogenicity  

 - Mutagenicity

 - Treatment of Poisoning

 - Symptoms & Management of Barbiturates, Morphine, Organophosphosphorus Compound  

 - Lead, Mercury & Arsenic Poisoning

                                                                                                                                                                              

    13.Chronopharmacology:

 - Definition of Rhythm & Cycles

 - Biological Clock & their Significance Leading to Chronotherapy

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